The global laboratory dry granulator market size was valued at USD 59.4 million in 2024. The market is projected to grow from USD 63.2 million in 2025 to USD 89.7 million by 2032, exhibiting a CAGR of 6.1% during the forecast period.

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A laboratory dry granulator is a specialized piece of equipment used for transforming powders into granules without liquid binders, primarily serving pharmaceutical, food, and chemical industries. This technology is critical for small-scale production, RD, and formulation development, particularly for moisture-sensitive or heat-sensitive materials where traditional wet granulation is unsuitable.

The market growth is driven by increasing pharmaceutical RD investments, projected to reach USD 260 billion globally by 2025, alongside stringent regulatory requirements for drug formulation consistency. While North America currently leads adoption due to strong biopharma sectors, Asia-Pacific shows the highest growth potential at 7.3% CAGR, fueled by expanding contract research organizations and generic drug manufacturing in India and China.The global laboratory dry granulator market is witnessing robust growth driven by increasing demand for efficient and precise granulation technologies in pharmaceutical and related industries. As pharmaceutical companies continue to invest heavily in research and development, the need for advanced dry granulation equipment that can handle moisture-sensitive and heat-sensitive compounds has become critical. Laboratory dry granulators offer a reliable, scalable, and cost-effective solution for producing consistent granules, essential for developing high-quality drug formulations. Additionally, growing regulatory emphasis on process consistency and quality control is further accelerating the adoption of dry granulation methods. With ongoing advancements in automation and process monitoring, the market is poised for significant expansion across regions, fueled by the pharmaceutical sector’s continuous innovation and stringent manufacturing standards.

MARKET DYNAMICS

MARKET DRIVERS

Growing Pharmaceutical RD Expenditure to Fuel Market Expansion

The pharmaceutical industry's increasing investment in research and development is a primary driver for the laboratory dry granulator market. With global pharmaceutical RD spending reaching approximately $250 billion annually, companies are prioritizing formulation development and process optimization. Dry granulation has become essential for APIs and excipients sensitive to moisture or heat, with over 35% of new drug candidates requiring this technology during early-phase development. The ability to produce uniform granules without solvents makes lab-scale dry granulators indispensable for formulation scientists working on novel drug delivery systems and stability testing.

National Bureau of Statistics of China , According to preliminary estimates, China's total expenditure on research and experimental development (RD) exceeded 3.6 trillion yuan in 2024, registering 3.6130 trillion yuan, an increase of 8.3 percent over the previous year

Regulatory Emphasis on Process Consistency to Stimulate Adoption

Stringent quality requirements from regulatory agencies are accelerating the adoption of laboratory dry granulators. Current Good Manufacturing Practice (cGMP) guidelines emphasize robustness in formulation processes, making granule consistency a critical parameter. Recent data shows that nearly 42% of pharmaceutical process deviations originate during granulation, prompting companies to invest in precise lab-scale equipment for parameter optimization. The technology's ability to maintain powder properties while improving flow characteristics aligns perfectly with regulatory expectations for reproducible manufacturing processes from early development stages.Regulatory bodies such as the FDA (U.S. Food and Drug Administration), EMA (European Medicines Agency), and other global authorities are increasingly emphasizing process consistency and quality control in pharmaceutical manufacturing.

Expansion of Contract Research Services to Enhance Market Growth

The rapid growth of pharmaceutical contract research organizations (CROs) presents significant opportunities for laboratory dry granulator manufacturers. With the CRO market expanding at approximately 8% annually, these service providers increasingly require versatile equipment capable of handling diverse formulations. Laboratory dry granulators offer CROs the flexibility to work with multiple client projects while maintaining distinct material characteristics. Recent equipment innovations in small-scale roller compaction and direct compression systems enable CROs to bridge formulation development with pilot-scale production more effectively than ever before.

MARKET RESTRAINTS

High Equipment Costs and Maintenance to Limit Market Penetration

While offering superior performance, laboratory dry granulators carry significant acquisition costs that restrain market growth. Premium laboratory-scale units can cost 3-4 times more than equivalent wet granulation equipment, with specialized models exceeding $150,000. Maintenance expenses further compound this challenge – sealed systems for potent compounds require frequent servicing, while precision rollers demand regular calibration. These factors create substantial barriers for small research facilities and academic institutions, limiting adoption primarily to well-funded pharmaceutical developers and established CROs.

Technical Limitations with Certain Formulations to Constrain Usage

Technical constraints with specific material properties present notable challenges for dry granulation adoption. Approximately 28% of pharmaceutical powders demonstrate poor compactibility without binders, requiring formulation modifications that complicate early-stage development. Cohesive powders tend to generate excessive fines during dry granulation, while some APIs exhibit reduced dissolution rates after compaction. These limitations force researchers to either accept suboptimal granule properties or invest additional time in formulation adjustments, slowing the technology's penetration into certain therapeutic categories.

MARKET CHALLENGES

Skilled Workforce Shortage to Impede Market Growth

The pharmaceutical industry faces an acute shortage of personnel trained in dry granulation technologies. Recent workforce analyses indicate that less than 15% of formulation scientists have hands-on experience with modern roller compaction systems. This skills gap becomes particularly problematic when scaling formulations from laboratory to production, where improper parameter translation can lead to costly process failures. The complexity of optimizing force, gap width, and feed rate combinations requires specialized knowledge that remains concentrated in a limited number of experienced professionals.

MARKET OPPORTUNITIES

Emerging Markets Expansion to Create New Growth Avenues

Pharmaceutical industry growth in Asia-Pacific regions presents substantial opportunities for laboratory dry granulator manufacturers. Countries like India and China are increasing their spending on pharmaceutical RD at rates exceeding 12% annually, creating demand for advanced formulation technologies. Local manufacturers transitioning toward regulated markets require equipment that can meet international quality standards, positioning laboratory dry granulators as critical investments for quality-focused emerging market players.

Continuous Manufacturing Adoption to Drive Innovation

The industry's shift toward continuous manufacturing creates compelling opportunities for next-generation laboratory dry granulators. Recent regulatory endorsements of continuous processes emphasize the need for equipment that seamlessly transitions from development to production. Manufacturers integrating process analytical technology (PAT) into laboratory granulators enable real-time monitoring critical for continuous systems, while advanced machine learning algorithms help predict scale-up parameters more accurately than traditional empirical approaches.

LABORATORY DRY GRANULATOR MARKET TRENDS

Pharmaceutical RD Investments to Drive Market Expansion

The laboratory dry granulator market is experiencing robust growth due to increasing investments in pharmaceutical research and development, particularly in novel drug formulation. As pharmaceutical companies and contract research organizations (CROs) develop more complex drug compounds, the need for efficient small-scale granulation solutions has intensified. The global pharmaceutical RD expenditure surpassed $250 billion in recent years, with a significant portion allocated to formulation development for solid dosage forms. Dry granulation is preferred for its ability to handle moisture-sensitive APIs while ensuring product stability during early-stage testing. Furthermore, regulatory agencies increasingly demand detailed formulation data before approving large-scale production, making laboratory-scale equipment indispensable.In 2023, Merck Co. made a considerable investment in research and development, spending more than $30 billion.

Other Trends

Automation and Process Optimization

The integration of advanced automation technologies into laboratory dry granulators is transforming formulation workflows. Modern systems now incorporate real-time monitoring sensors and AI-driven process optimization to improve granule consistency and reduce material waste. In precision-critical applications such as controlled-release formulations, automated adjustment of compaction force and feed rates has improved yield by up to 20% compared to conventional systems. These technological upgrades are particularly valuable for contract manufacturers handling multiple formulation projects simultaneously, where equipment flexibility and data reproducibility are paramount.

Material Science Advancements Open New Possibilities

The market is witnessing growing adoption of laboratory dry granulators for processing novel excipients and composite materials in industries beyond pharmaceuticals. In the food sector, manufacturers are utilizing these systems to develop fortified nutrient granules with precisely controlled release profiles. Similarly, specialty chemical producers employ dry granulation to create uniform catalyst carriers for industrial applications. Equipment manufacturers have responded by developing specialized models with enhanced corrosion resistance and broader pressure ranges to accommodate diverse material properties. This cross-industry application trend is expected to contribute over 30% of new market growth through 2032.

Key Industry Players

Market Leaders Focus on Innovation and Expansion to Drive Growth

The global Laboratory Dry Granulator market features a competitive yet fragmented landscape, with established players and regional manufacturers vying for market share. Fitzpatrick emerges as a dominant force, leveraging its extensive expertise in particle size reduction technology and strong foothold in pharmaceutical applications. The company's emphasis on modular granulator designs and compliance with cGMP standards has solidified its position in regulated industries.

Hosokawa Micron and Alexanderwerk collectively hold approximately 28% of the market share as of 2024, according to industry estimates. Their advantage stems from continuous RD investments - Hosokawa's recent launch of the Granulex™ series demonstrates this commitment, featuring improved compaction control and energy efficiency. Meanwhile, Freund Corporation has been gaining traction through its specialized Vector series granulators tailored for pharmaceutical research applications.

Asia-Pacific manufacturers such as Beijing LongliTech and Yenchen Machinery are rapidly expanding their presence, capitalizing on lower production costs and growing domestic pharmaceutical sectors. These companies have been particularly successful in supplying affordable laboratory-scale equipment to emerging markets while gradually improving their technological capabilities to compete globally.

European manufacturers including GERTEIS and L.B. Bohle maintain strong positions in premium market segments, differentiating through precision engineering and automation features. Their focus on ICH Q8 compliance and PAT (Process Analytical Technology) integration aligns well with the stringent requirements of European pharmaceutical manufacturers.

Strategic movements in the market include Cadmac's recent acquisition of complementary technology patents and Prism Pharma Machinery's expansion into North American markets through distribution partnerships. These developments indicate an industry-wide push towards technological differentiation and geographic diversification to capture growth in the projected $89.7 million market by 2032.

2023, RFI Ingredients (USA) introduced TruHD dry granulation technology, aimed at high-speed tablet/capsule manufacturing

2025, Beijing LongliTech showcased its products at the Maghreb Pharma Expo 2025 held in Algiers, Algeria, from April 22 to 24, 2025. This participation highlights the company's efforts to expand its presence in international markets

January 2020, Hosokawa Alpine AG, a group company of Hosokawa Micron, acquired the Solids Solutions Group.The acquisition led to the formation of "Hosokawa Solids Solutions GmbH," enhancing Hosokawa's portfolio in bulk solids handling

List of Key Laboratory Dry Granulator Companies Profiled

• Fitzpatrick (U.S.)
• Hosokawa Micron (Japan)
• Alexanderwerk (Germany)
• Freund Corporation (Japan)
• Beijing LongliTech (China)
• GERTEIS (Switzerland)
• L.B. Bohle (Germany)
• Yenchen Machinery (Taiwan)
• WelchDry (U.S.)
• Cadmach (India)
• Canaan Technology (China)
• Bepex (Germany)
• Prism Pharma Machinery (India)
• KEYUAN (China)
• KaiChuang Machinery (China)

Segment Analysis:

By Capacity

Production Capacity 30-200Kg/Hour Segment Leads Due to Optimal Balance Between Efficiency and Flexibility

The market is segmented based on production capacity into:

• Production Capacity 30Kg/Hour

o    Primarily used in small-scale research laboratories and academic settings

• Production Capacity 30-200Kg/Hour

o    Most popular segment for pharmaceutical formulation development

• Production Capacity 200Kg/Hour

o    Used in pilot plants and small-scale manufacturing facilities

By Application

Pharmaceutical Sector Dominates Market Demand Due to Extensive RD Activities

The market is segmented based on application into:

• Pharmacy

o    Drug formulation development

o    Solid dosage form research

• Chemical Industry

o    Specialty chemicals production

o    Catalyst development

• Food

o    Food additive research

o    Nutritional supplement development

• Others

By Type

Roller Compaction Technology Remains Market Leader for Dry Granulation Processes

The market is segmented based on technology into:

• Roller Compaction

o    Most widely adopted technology for pharmaceutical applications

• Slugging

o    Traditional method suitable for smaller batches

• Advanced Dry Granulation

o    Incorporates automation and process control features

By End User

Research Institutions Show Significant Adoption for Formulation Development

The market is segmented based on end user into:

• Pharmaceutical Companies
• Contract Research Organizations (CROs)
• Academic and Research Institutions
• Food Technology Companies
• Chemical Manufacturers

Regional Analysis: Laboratory Dry Granulator Market

North America
The North American laboratory dry granulator market is driven by strong pharmaceutical RD investments and stringent regulatory standards set by the FDA. The U.S. pharmaceutical sector alone invests over $100 billion annually in research, fueling demand for precise small-scale granulation equipment. While the region leads in technological adoption, high equipment costs and skilled labor requirements create challenges for smaller research facilities. Many pharmaceutical and biotech companies favor compact, automated granulators with real-time monitoring capabilities to streamline formulation development. Environmental regulations promoting solvent-free processes further boost dry granulation adoption over wet methods.

Europe
Europe's market thrives on its robust pharmaceutical manufacturing sector and tight EMA quality standards requiring thorough formulation testing. Germany and Switzerland, housing major pharmaceutical hubs, account for over 40% of regional demand. The market sees growing preference for modular granulators that allow easy integration with other lab equipment. However, pricing pressure from Asian manufacturers and lengthy equipment validation processes sometimes hinder adoption. Sustainability initiatives across the EU are accelerating the shift from wet to dry granulation, particularly for heat-sensitive biopharmaceutical applications.

Asia-Pacific
The APAC region represents the fastest-growing market, projected to expand at 7.2% CAGR through 2032, driven by China and India's booming pharmaceutical industries. Cost-effective equipment from domestic manufacturers captures about 60% of local demand, though multinationals still prefer premium imported machines. While production capacity below 30kg/hour dominates currently, research facilities are gradually shifting toward mid-range 30-200kg/hour models. The growing contract research sector and increasing API production are creating new opportunities across the region. Challenges include inconsistent power supply in some areas and limited service networks for specialized equipment.

South America
South America's market shows steady growth led by Brazil's developing pharmaceutical sector and Argentina's focus on generic drug production. Economic instability in some countries limits capital expenditure on advanced equipment, keeping demand concentrated in basic benchtop models. The growing nutraceutical industry presents new application areas for dry granulators. Infrastructure limitations and dependence on imported equipment (particularly from Europe) contribute to longer lead times and higher operational costs. Recent trade agreements may improve equipment accessibility in the coming years.

Middle East Africa
This emerging market is gaining traction as countries like Saudi Arabia and UAE invest in pharmaceutical manufacturing capabilities. Government initiatives to build research infrastructure are driving first-time equipment purchases, though adoption remains modest compared to other regions. The market shows preference for durable, low-maintenance models suited for harsh climates. While international pharmaceutical companies establish local facilities, limited technical expertise in dry granulation techniques slows broader implementation. Regional collaborations and training programs may help overcome this barrier in the long term.

Report Scope

This market research report offers a holistic overview of global and regional markets for the forecast period 2025–2032. It presents accurate and actionable insights based on a blend of primary and secondary research.

Key Coverage Areas:

• ✅ Market Overview

o    Global and regional market size (historical forecast)

o    Growth trends and value/volume projections

• ✅ Segmentation Analysis

o    By product type or category

o    By application or usage area

o    By end-user industry

o    By distribution channel (if applicable)

• ✅ Regional Insights

o    North America, Europe, Asia-Pacific, Latin America, Middle East Africa

o    Country-level data for key markets

• ✅ Competitive Landscape

o    Company profiles and market share analysis

o    Key strategies: MA, partnerships, expansions

o    Product portfolio and pricing strategies

• ✅ Technology Innovation

o    Emerging technologies and RD trends

o    Automation, digitalization, sustainability initiatives

o    Impact of AI, IoT, or other disruptors (where applicable)

• ✅ Market Dynamics

o    Key drivers supporting market growth

o    Restraints and potential risk factors

o    Supply chain trends and challenges

• ✅ Opportunities Recommendations

o    High-growth segments

o    Investment hotspots

o    Strategic suggestions for stakeholders

• ✅ Stakeholder Insights

o    Target audience includes manufacturers, suppliers, distributors, investors, regulators, and policymakers

FREQUENTLY ASKED QUESTIONS:

▶ What is the current market size of Global Laboratory Dry Granulator Market?

The global laboratory dry granulator market was valued at USD 59.4 million in 2024 and is projected to reach USD 89.7 million by 2032, growing at a CAGR of 6.1% during the forecast period.

▶ Which key companies operate in Global Laboratory Dry Granulator Market?

Key players include Fitzpatrick, Hosokawa, Alexanderwerk, Freund Corporation, Beijing LongliTech, GERTEIS, L.B. Bohle, Yenchen Machinery, WelchDry, and Cadmach, among others.

▶ What are the key growth drivers?

Key growth drivers include rising pharmaceutical RD investments, stringent regulatory requirements for drug formulations, and technological advancements in dry granulation equipment.

▶ Which region dominates the market?

North America currently leads the market, while Asia-Pacific is expected to witness the fastest growth due to expanding pharmaceutical manufacturing capabilities.

▶ What are the emerging trends?

Emerging trends include automation in granulation processes, integration of Industry 4.0 technologies, and development of compact, high-efficiency laboratory granulators.

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